Dean Bobo

Associate Bioinformatician

 
Dean is a bioinformatician at the Center for Genomic Health. He is interested in data science, genomics, and next-generation sequencing technologies. He previously worked a Bioinformatics Scientist in Department of Ecology and Evolution at Stony Brook University. There he worked with Dr. Brenna Henn, Dr. Krishna Veeramah, and Dr. Jesse Hollister on a wide variety of projects ranging from the QCing of next-generation sequencing to the transmission of bacteria in lemur populations. He is currently working on inferring continental and local ancestry on individuals sequenced by NHGRI’s Genome Sequencing Program. He is also building an enterprise-grade pipeline to annotate genetic variation identified by next-generation sequencing for clinical uses. Dean trained at a number of illustrious institutions including Ramapo College of New Jersey.

Publications

 
Understanding 6th-century barbarian social organization and migration through paleogenomics.
Amorim CEG, Vai S, Posth C, Modi A, Koncz I, Hakenbeck S, La Rocca MC, Mende B, Bobo D, Pohl W, Baricco LP, Bedini E, Francalacci P, Giostra C, Vida T, Winger D, von Freeden U, Ghirotto S, Lari M, Barbujani G, Krause J, Caramelli D, Geary PJ, Veeramah KR.
Nat Commun. 2018 Sep 11;9(1):3547. doi: 10.1038/s41467-018-06024-4.
PMID: 30206220

No Evidence for Recent Selection at FOXP2 among Diverse Human Populations.
Atkinson EG, Audesse AJ, Palacios JA, Bobo DM, Webb AE, Ramachandran S, Henn BM.
Cell. 2018 Sep 6;174(6):1424-1435.e15. doi: 10.1016/j.cell.2018.06.048. Epub 2018 Aug 2.
PMID: 30078708

Ancient European dog genomes reveal continuity since the Early Neolithic.
Botigué LR, Song S, Scheu A, Gopalan S, Pendleton AL, Oetjens M, Taravella AM, Seregély T, Zeeb-Lanz A, Arbogast RM, Bobo D, Daly K, Unterländer M, Burger J, Kidd JM, Veeramah KR.
Nat Commun. 2017 Jul 18;8:16082. doi: 10.1038/ncomms16082.
PMID: 28719574

Fine-Scale Human Population Structure in Southern Africa Reflects Ecogeographic Boundaries.
Uren C, Kim M, Martin AR, Bobo D, Gignoux CR, van Helden PD, Möller M, Hoal EG, Henn BM.
Genetics. 2016 Sep;204(1):303-14. doi: 10.1534/genetics.116.187369. Epub 2016 Jul 29.
PMID: 27474727

Early Neolithic genomes from the eastern Fertile Crescent.
Broushaki F, Thomas MG, Link V, López S, van Dorp L, Kirsanow K, Hofmanová Z, Diekmann Y, Cassidy LM, Díez-Del-Molino D, Kousathanas A, Sell C, Robson HK, Martiniano R, Blöcher J, Scheu A, Kreutzer S, Bollongino R, Bobo D, Davudi H, Munoz O, Currat M, Abdi K, Biglari F, Craig OE, Bradley DG, Shennan S, Veeramah K, Mashkour M, Wegmann D, Hellenthal G, Burger J.
Science. 2016 Jul 29;353(6298):499-503. doi: 10.1126/science.aaf7943. Epub 2016 Jul 14.
PMID: 27417496

Early farmers from across Europe directly descended from Neolithic Aegeans.
Hofmanová Z, Kreutzer S, Hellenthal G, Sell C, Diekmann Y, Díez-Del-Molino D, van Dorp L, López S, Kousathanas A, Link V, Kirsanow K, Cassidy LM, Martiniano R, Strobel M, Scheu A, Kotsakis K, Halstead P, Triantaphyllou S, Kyparissi-Apostolika N, Urem-Kotsou D, Ziota C, Adaktylou F, Gopalan S, Bobo DM, Winkelbach L, Blöcher J, Unterländer M, Leuenberger C, Çilingiroğlu Ç, Horejs B, Gerritsen F, Shennan SJ, Bradley DG, Currat M, Veeramah KR, Wegmann D, Thomas MG, Papageorgopoulou C, Burger J.
Proc Natl Acad Sci U S A. 2016 Jun 21;113(25):6886-91. doi: 10.1073/pnas.1523951113. Epub 2016 Jun 6.
PMID: 27274049

Exome capture from saliva produces high quality genomic and metagenomic data.
Kidd JM, Sharpton TJ, Bobo D, Norman PJ, Martin AR, Carpenter ML, Sikora M, Gignoux CR, Nemat-Gorgani N, Adams A, Guadalupe M, Guo X, Feng Q, Li Y, Liu X, Parham P, Hoal EG, Feldman MW, Pollard KS, Wall JD, Bustamante CD, Henn BM.
BMC Genomics. 2014 Apr 4;15:262. doi: 10.1186/1471-2164-15-262.
PMID: 24708091

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